Scout | PAR-24-133: NIH Small Business Transition Grants for New Entrepreneurs (STTR R41/R42, no clinical trials)

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grant PAR-24-133

NIH Small Business Transition Grants for New Entrepreneurs (STTR R41/R42, no clinical trials)

Summary

NIH invites U.S. small businesses to apply for STTR Phase I or Fast-Track grants that place early-career scientists as PD/PIs to develop health technologies with commercial potential. Funding supports R&D plus robust mentorship and entrepreneurship training; clinical trials are not allowed. Multiple NIH Institutes participate with institute-specific priorities.

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, also known as America's Seed Fund, are one of the largest sources of early-stage capital for technology commercialization in the United States. These programs enable US-owned and operated small …

Funding Source

Agency: National Institutes of Health

Phase: Phase I

Phase: Phase II

Awards & funding

Award Ceiling: $2.0M

Eligibility

United States Small Business Concerns (SBCs) – for‑profit entities with a U.S. place of business that operate primarily in the U.S. or make a significant contribution to the U.S. economy; legal forms include individual proprietorships, partnerships, LLCs, corporations, joint ventures, associations, trusts, or cooperatives; <=500 employees including affiliates

Joint Ventures of eligible small business concerns – JV must have <50% participation by foreign business entities; each entity in the JV must independently meet the SBIR/STTR ownership and control criteria; JV subject to 13 CFR 121.705(b) registration/proposal requirements

SBCs majority‑owned by multiple venture capital operating companies, hedge funds, or private equity firms – SBIR ONLY (not eligible for STTR); no single VCOC/hedge fund/private equity firm may own >50% unless that firm itself qualifies as a small business >50% owned and controlled by U.S. individuals

Tribal/Native SBCs – small business concerns >50% owned by an Indian tribe, Alaska Native Corporation (ANC), or Native Hawaiian Organization (NHO), or a wholly owned business entity of such tribe/ANC/NHO

Core organizational eligibility:

Only U.S. Small Business Concerns (SBCs) may apply. At the time of award (Phase I and Phase II) an SBC must: (1) be organized for profit with a place of business in the United States and operate primarily in the U.S. or make a significant contributio…

Dates

Application Window Closes: April 5, 2027

Opportunity Released: April 25, 2024

Open for Submission: April 25, 2024

Submission Deadline: April 5, 2027

Supporting links

National Institutes of Health

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