Scout | PAR-25-199: Develop next-generation human nervous-system microphysiological systems (R21, no clinical trials)

This opportunity is no longer accepting applications.

grant PAR-25-199

Develop next-generation human nervous-system microphysiological systems (R21, no clinical trials)

Summary

This NIH R21 NOFO funds technology-focused projects to build advanced human cell–derived microphysiological systems (MPS)—including organoids, tissue-chips, or xenografts—that better reproduce circuit-level structure, maturation, connectivity and long-term function of brain, spinal cord, or sensory organs. Applications should prioritize improving assay fidelity, reproducibility, multi-lineage …

Human cell-based assays (e.g., using induced pluripotent stem cells) hold promise for identifying molecular, cellular and circuit defects, identifying novel targets and developing new therapeutics for patients with complex brain and other nervous system disorders. However, the methods to generat…

Funding Source

Agency: National Institutes of Health

Sub-agency: National Institute on Aging

Awards & funding

Total Funding: $200,000

Award Ceiling: $275,000

Award Amount: $200,000

Eligibility

Nonprofits Other Than Institutions of Higher Education – without 501(c)(3) IRS Status

Higher Education Institutions – Private Institutions of Higher Education

For-Profit Organizations – Other than Small Businesses

U.S. Territory or Possession Governments/Entities

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Faith-based or Community-based Organizations

Regional Organizations

Non-domestic (non-U.S.) Entities (Foreign Organizations)

Foreign entities: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic components of U.S. organizations are eligible. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Required registrations (must be completed/active be…

Dates

Opportunity Released: November 6, 2024

Open for Submission: November 6, 2024

Submission Deadline: January 7, 2026

Application Window Closes: January 7, 2026

Supporting links

National Institutes of Health

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