Scout | PAR-25-225: IGNITE R61/R33: Preclinical Characterization and In‑Vivo Efficacy for Neurotherapeutics (No Clinical Trials)

grant PAR-25-225

IGNITE R61/R33: Preclinical Characterization and In‑Vivo Efficacy for Neurotherapeutics (No Clinical Trials)

Summary

NINDS IGNITE R61/R33 grants fund translational preclinical work to characterize therapeutic agents (small molecules, biologics, gene/cell and emerging modalities), perform PK/PD studies in the R61, and demonstrate in‑vivo efficacy in the R33. Awards are phased and milestone-driven: the R61 supports preparatory characterization and PK work and progress to the R33 depends on meeting quantitative…

This notice of funding opportunity (NOFO) is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to encourage the translation of research discoveries into new treatments for disorders that fall under the NINDS mission. Supported therapeutic agents include small…

Funding Source

Agency: National Institutes of Health

Sub-agency: National Institute of Neurological Disorders and Stroke

Awards & funding

Award Ceiling: $499,000

Eligibility

Regional Organizations

Higher Education Institutions: Private Institutions of Higher Education

Nonprofits (Other than Institutions of Higher Education): Nonprofits without 501(c)(3) IRS Status

For-Profit Organizations: For-Profit Organizations (Other than Small Businesses)

Federal Government: Eligible Agencies of the Federal Government

U.S. Territory or Possession

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Faith-based or Community-based Organizations

Non-domestic (non-U.S.) Entities (Foreign Organizations)

Non-domestic (non-U.S.) components of U.S. Organizations

Foreign/Non-domestic eligibility: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Required regist…

Dates

Opportunity Released: November 4, 2024

Open for Submission: November 4, 2024

Submission Deadline: October 20, 2027

Application Window Closes: October 20, 2027

Supporting links

National Institutes of Health

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