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forecast PA-127-102

NIH Small Business Technology Transfer (STTR) Grants (R41/R42): Clinical Trial Optional

NIH plans to release a Notice of Funding Opportunity (NOFO) inviting U.S. small businesses to submit STTR Phase I, Phase II, Direct to Phase II (NIH only), and NIH-only Fast-Track applications using the R41/R42 activity code. This is a planning notice—applications are not being solicited yet—so potential applicants can form collaborations and prepare responsive proposals. Work should align wit…

The National Institutes of Health (NIH), including the following NIH Institutes and Centers (ICs): NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, ORIP, NCI and ORWH, intends to publish a Notice of F…

Funding Source

Agency: National Institutes of Health
Program: STTR

Eligibility

Small business
Startup
Biotechnology
Healthcare
Research

The annual SBIR/STTR Omnibus Solicitation encourages investigator-initiated grant applications across a broad range of research areas. Eligible U.S. small businesses should have the capabilities and technological expertise to contribute to the research and development missions of the awarding NI…

Dates

Estimated Post Date: June 1, 2026
Estimated Application Due Date: September 5, 2026
Estimated Award Date: March 1, 2027

Supporting links

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