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grant RFA-HL-26-014

NHLBI SBIR Phase IIB Bridge: Funding to Commercialize Heart, Lung, Blood, and Sleep Technologies

NHLBI’s SBIR Phase IIB Bridge Award provides follow-on funding to small businesses to advance prior SBIR/STTR Phase II projects in heart, lung, blood, and sleep health toward commercialization. Applicants must secure third-party investment that equals or exceeds the NHLBI request and propose work such as regulatory and clinical validation; R44 clinical trial is optional. Projects must extend p…

Since its inception in 1982, the NIH SBIR program has provided the small business community with seed funding to support the development of a broad array of commercial products to detect, diagnose, treat, and prevent disease. It provides an important funding mechanism for bringing new interventi…

Funding Source

Agency: National Heart, Lung, and Blood Institute
Sub-agency: National Institutes of Health

Awards & funding

Total Funding: $52.5M
Award Ceiling: $3.5M

Eligibility

United States Small Business Concerns (SBCs) — for‑profit, U.S.-based small businesses with no more than 500 employees (including affiliates) that operate primarily in the U.S. or make a significant contribution to the U.S. economy
SBCs majority-owned and controlled (>50%) by U.S. citizens or permanent resident aliens, or by other qualifying U.S.-owned business concerns
SBCs owned by an Indian tribe, Alaska Native Corporation (ANC), or Native Hawaiian Organization (NHO), or a wholly owned business entity of such tribe/ANC/NHO
SBCs majority-owned by multiple venture capital operating companies (VCOCs), hedge funds, or private equity firms (SBIR-only), provided no single such firm owns >50% unless that firm itself qualifies as a U.S.-owned SBC
Joint ventures of eligible small business concerns (each JV entity must meet SBA SBIR ownership/control criteria; JV must have <50% participation by foreign business entities and comply with SBA §121.705(b) if VC-owned concerns are involved)

Only United States small business concerns (SBCs) are eligible applicants for this NHLBI SBIR Phase IIB Bridge Award NOFO (RFA-HL-26-014). Key SBA/NIH eligibility conditions include:

Small business definition and ownership/control:

  • Organized for profit with a place of busines…

Dates

Opportunity Released: November 18, 2024
Open for Submission: November 18, 2024
Submission Deadline: February 26, 2027
Application Window Closes: February 26, 2027

Supporting links

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