Developing next-generation human nervous system microphysiological systems (R01, no clinical trials)
This R01 NOFO supports technology-focused research to develop advanced human cell–derived microphysiological systems (e.g., organoids, tissue chips, xenografts) that better replicate brain, spinal cord, or sensory circuit maturation, connectivity, and long-term function. Projects should prioritize improving physiological fidelity, robustness, and reproducibility of circuit-level readouts rathe…
Human cell-based assays (e.g., using induced pluripotent stem cells) hold promise for identifying molecular, cellular, and circuit defects, identifying novel targets and developing new therapeutics for patients with complex brain and other nervous system disorders. However, the methods to genera…
Funding Source
Eligibility
- Foreign entities: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
- Required registrations …
Dates
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