Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed)
This R01 NOFO supports technology-focused research to develop advanced human cell–derived microphysiological systems (e.g., organoids, tissue chips, xenografts) that better replicate brain, spinal cord, or sensory circuit maturation, connectivity, and long-term function. Projects should prioritize improving physiological fidelity, robustness, and reproducibility of circuit-level readouts rathe…
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