Scout | PAR-25-211: R61/R33: Mechanistic Research to Enable Precision Probiotic Therapies (Clinical Trial Optional)

grant PAR-25-211

R61/R33: Mechanistic Research to Enable Precision Probiotic Therapies (Clinical Trial Optional)

Summary

This NIH NOFO funds milestone-driven, biphasic mechanistic research to identify person-specific factors (e.g., microbiome, immune status, sex, age, diet, genetics) that explain variable responses to probiotic interventions. The R61 phase supports observational or secondary-data studies to find host patterns linked to probiotic effects; the R33 phase tests causality in rigorous mechanistic stud…

The purpose of this notice of funding opportunity (NOFO) is to support highly innovative mechanistic research to accelerate the development of effective precision probiotic interventions using a milestone-driven, biphasic award mechanism. It aims to identify, understand, and develop strategies t…

Funding Source

Agency: National Institutes of Health

Sub-agency: National Center for Complementary and Integrative Health

Awards & funding

Award Ceiling: $350,000

Eligibility

Public/State-Controlled Institutions of Higher Education

Private Institutions of Higher Education

Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)

Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

Small Businesses

For-Profit Organizations (Other than Small Businesses)

Local Governments

State Governments

County Governments

City or Township Governments

Special District Governments

Indian/Native American Tribal Governments (Federally Recognized)

Indian/Native American Tribal Governments (Other than Federally Recognized)

Eligible Agencies of the Federal Government

U.S. Territories or Possessions

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Faith-based or Community-based Organizations

Regional Organizations

Foreign/Non-domestic entities are NOT eligible to apply: Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statem…

Dates

Opportunity Released: October 31, 2024

Open for Submission: October 31, 2024

Submission Deadline: June 2, 2027

Application Window Closes: June 2, 2027

Supporting links

National Institutes of Health

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