Scout | RFA-TR-23-017: Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)

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grant RFA-TR-23-017

Miniaturization and Automation of Tissue Chip Systems (MATChS) (U43/U44 Clinical Trial Not Allowed)

NCATS invites US small businesses to develop benchtop, portable, automated microphysiological (tissue chip/organ-on-chip) systems with integrated sensors, flow control, and software for high throughput, reliable readouts of tissue health and function. SBIR funding is available via U43/U44 Phase I, Phase II, Fast-Track, and Direct-to-Phase II cooperative agreements; projects are milestone-drive…

Source

Agency: National Institutes of Health

Sub-agency: National Center for Advancing Translational Sciences

Award

Award Floor: $350,000

Dates

Opportunity Released: November 21, 2023

Open for Submission: November 21, 2023

Submission Deadline: February 23, 2026

Application Window Closes: February 23, 2026

Eligibility

Small business

U.S. SBCs owned and controlled (>50%) by: U.S. citizens or permanent resident aliens; other U.S.-owned SBCs; an Indian tribe, Alaska Native Corporation (ANC), or Native Hawaiian Organization (NHO) (or a wholly owned entity of such tribe/ANC/NHO); or any combination thereof

SBIR-only: U.S. SBCs majority-owned by multiple venture capital operating companies (VCOCs), hedge funds, or private equity firms (no single firm may own >50% unless it itself qualifies as a U.S.-owned SBC)

Joint ventures of eligible entities – a joint venture in which each entity to the joint venture meets the SBC ownership/control requirements (and complies with SBA registration/proposal rules for VCOC-owned structures)

United States Small Business Concerns (SBCs) – for‑profit entities with a U.S. place of business that primarily operate in the U.S. and have no more than 500 employees (including affiliates)

Keywords

sbir

small business

tissue chips

organ-on-chip

microphysiological systems

automation

miniaturization

ncats

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