Scout | RFA-TR-23-017: SBIR to miniaturize and automate tissue and organ-on-chip systems (U43/U44; no clinical trials)

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grant RFA-TR-23-017

SBIR to miniaturize and automate tissue and organ-on-chip systems (U43/U44; no clinical trials)

Summary

NCATS invites US small businesses to develop benchtop, portable, automated microphysiological (tissue chip/organ-on-chip) systems with integrated sensors, flow control, and software for high throughput, reliable readouts of tissue health and function. SBIR funding is available via U43/U44 Phase I, Phase II, Fast-Track, and Direct-to-Phase II cooperative agreements; projects are milestone-drive…

This Notice of Funding Opportunity (NOFO) invites eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, Phase II, Fast-Track and Direct to Phase II grant applications. The funding opportunity will utilize a U43/U44 cooperative agreemen…

Funding Source

Agency: National Center for Advancing Translational Sciences

Sub-agency: National Institutes of Health

Phase: Phase II

Phase: Phase I

Awards & funding

Award Floor: $350,000

Eligibility

U.S. SBCs owned and controlled (>50%) by: U.S. citizens or permanent resident aliens; other U.S.-owned SBCs; an Indian tribe, Alaska Native Corporation (ANC), or Native Hawaiian Organization (NHO) (or a wholly owned entity of such tribe/ANC/NHO); or any combination thereof

SBIR-only: U.S. SBCs majority-owned by multiple venture capital operating companies (VCOCs), hedge funds, or private equity firms (no single firm may own >50% unless it itself qualifies as a U.S.-owned SBC)

Joint ventures of eligible entities – a joint venture in which each entity to the joint venture meets the SBC ownership/control requirements (and complies with SBA registration/proposal rules for VCOC-owned structures)

United States Small Business Concerns (SBCs) – for‑profit entities with a U.S. place of business that primarily operate in the U.S. and have no more than 500 employees (including affiliates)

Only U.S. Small Business Concerns (SBCs) are eligible to apply for this NOFO (SBIR cooperative agreement). Key SBA/NIH eligibility conditions include: (1) Organized for profit; legal forms may include proprietorship, partnership, LLC, corporation, joint venture, association, trust, or cooperativ…

Dates

Opportunity Released: November 21, 2023

Open for Submission: November 21, 2023

Submission Deadline: February 23, 2026

Application Window Closes: February 23, 2026

Supporting links

National Institutes of Health

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