RNA Modifications Driving Oncogenesis (RNAMoDO; U01 Clinical Trial Not Allowed)
This grant aims to support research exploring how RNA modifications contribute to cancer development, particularly through changes in protein production within cells. It focuses on understanding how modifications in different types of RNA (mRNA, tRNA, and rRNA) influence cancer progression and response to treatment. Since this area is complex, involving interactions between various RNA modific…
The overarching objective of this concept is to promote mechanistic research in the emerging area of RNA modifications that drive oncogenesis, with a focus on the central role of RNA modifications in translational reprogramming of cancer cells. RNA modifications have been recognized to exert a s…
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