Scout | PAR-25-183: Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

grant PAR-25-183

Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

This NOFO funds single-phase, early-stage clinical trials testing pharmacologic agents with novel mechanisms or neuromodulatory devices to treat symptoms or functional domains in people with mental illness, including prodromal cases. Proposals must test the presumed mechanism of action and demonstrate dose-dependent neurophysiological, clinical, or behavioral effects. Studies may target pediat…

Source

Agency: National Institutes of Health

Sub-agency: National Institute of Mental Health

Award

Total Funding: $27M

Dates

Opportunity Released: November 26, 2024

Eligibility

Government

Individual

Energy

Research

Nonprofit

Small business

Tribal

University

U.S. Territories and Possessions

Independent School Districts

Public Housing Authorities/Indian Housing Authorities

Faith-based Organizations

Community-based Organizations

Regional Organizations

Foreign Organizations (Non-domestic entities)

Native American Tribal Organizations (other than Federally recognized tribal governments)

Private Institutions of Higher Education

Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations (Other than Small Businesses)

Federal Government (Eligible Agencies of the Federal Government)

Keywords

mental disorders

neuromodulatory devices

target engagement

exploratory medicine

cns pharmacodynamics

circuit-based targets

dose-response testing

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Documents

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