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forecast PA-27-101

NIH SBIR Phase IIB Strategic Breakthrough (R44) — Valley of Death funding for prior Phase II awardees

NIH plans to issue an SBIR Phase IIB Strategic Breakthrough (R44) NOFO to help small businesses bridge the “Valley of Death” between Phase II R&D and real market/customer access, especially for projects needing extra time such as regulatory work, complex tools, or clinical/behavioral interventions. However, the notice states applications are not being solicited at this time, and eligibilit…

The National Institutes of Health (NIH), including the following NIH Institutes and Centers (ICs): NCI, NEI, NHLBI, NIA, NIAAA, NIAID, NICHD, NIDDK, NIGMS, NIMH, NIMHD, NINDS, NCATS, ORIP, and ORWH, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small …

Funding Source

Agency: National Institutes of Health
Program: SBIR

Eligibility

Small business
Startup
Healthcare
Research

Dates

Estimated Post Date: June 1, 2026
Estimated Application Due Date: September 5, 2026
Estimated Award Date: March 1, 2027

Supporting links

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