Notice of Special Interest (NOSI): Pharmacogenomic Approaches to Enhancing HIV and Substance Use Disorder (SUD) Treatment Strategies, A jump into Precision Medicine.
This grant opportunity seeks research proposals on the effects of human genetic variants on the treatment of HIV in people living with HIV (PLWH) who also have substance use disorders (SUD). The goal is to explore how these genetic differences affect the metabolism, effectiveness, and safety of HIV medications, particularly in interaction with substances of abuse and their treatments. This res…
Variable responses to ART are due at least in part to human genetic variants that affect drug metabolism, drug disposition, and off-site drug targets. Defining effects of human genetic variants on HIV treatment toxicity, efficacy, and pharmacokinetics has far-reaching implications. Substances of…
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