Mitochondrial Mechanisms in Aging with HIV and Substance Use (R01, No Clinical Trials)
This R01 funds basic and preclinical studies to uncover how mitochondrial dysfunction links HIV infection, antiretroviral therapy, and substance use to neurocognitive decline and immune aging. The goal is to identify protective and harmful pathways, biomarkers, and targets that could lead to interventions for people aging with HIV and substance use disorders (clinical trials are not allowed).<…
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