Mitochondrial-associated Mechanisms of Neuropathological and Immunodeficient Aging in the Context of HIV and SUD (R01 Clinical Trials Not Allowed)
This R01 funds basic and preclinical studies to uncover how mitochondrial dysfunction links HIV infection, antiretroviral therapy, and substance use to neurocognitive decline and immune aging. The goal is to identify protective and harmful pathways, biomarkers, and targets that could lead to interventions for people aging with HIV and substance use disorders (clinical trials are not allowed).<…
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