Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R21 Clinical Trial Not Allowed)
This grant opportunity aims to support research focused on tackling HIV infection in individuals with substance use disorders (SUD). It seeks proposals for projects that will: (1) Identify targets and pathways to suppress HIV transcription in HIV reservoirs, such as the central nervous system, in people with SUD. (2) Apply new drug discovery methods to find compounds that could help suppress H…
HIV infection and substance use are comorbid conditions that bidirectionally and synergistically influence the deleterious outcomes in people who suffer from substance use disorders (SUD). The persistence and transcriptional reactivation of HIV lead to the development of neuropathological compl…
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