Elucidating Immunometabolic Responses to HIV Infection that Increase TB or HBV Risk (R21 Clinical Trial Not Allowed)
This grant opportunity is focused on funding research that explores how changes in immune system metabolism caused by HIV impact the regulation of immune cells, their interactions, responses to treatments, and the progression of tuberculosis (TB) and hepatitis B (HBV) diseases.
People living with HIV (PLWH) are 18-times more likely to develop active tuberculosis (TB) than people without HIV, and TB is the leading cause of death in PLWH. Likewise, nearly eight percent of PLWH are also living with chronic hepatitis B virus (HBV), and they have an 8-10% risk of developing…
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Foreign/Non-domestic eligibility: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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