grant PAR:PAR-25-449.html

Mind-Body Interventions to Improve Emotional Well-Being and Whole Person Health (R61/R33; Clinical Trial Required)

NCCIH is soliciting R61/R33 applications for randomized, well-powered mechanistic clinical trials that test how mind-and-body interventions (e.g., mindfulness, yoga, acupuncture) modify innovative emotional well-being (EWB) mechanisms as the primary outcome and how those changes relate to Whole Person Health measured by the WPHI (secondary outcome). Applicants must provide strong preliminary d…

The National Center for Complementary and Integrative Health (NCCIH) announces this Notice of Funding Opportunity (NOFO) to solicit applications for research on how mind and body interventions through psychological and/or physical practices (e.g., mindfulness meditation, yoga, acupuncture, massa…

Funding Source

Agency: Department of Health and Human Services

Awards & funding

Total Funding: $2M
Award Ceiling: $475,000

Eligibility

Regional Organizations
Faith-based or Community-based Organizations
Public Housing Authorities/Indian Housing Authorities
Independent School Districts
U.S. Territory or Possession
Indian/Native American Tribal Governments (Federally Recognized)
Local Governments
Special District Governments
City or Township Governments
County Governments
Small Businesses
Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
Public/State Controlled Institutions of Higher Education

Foreign/Non-domestic entities are NOT eligible: Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allow…

Dates

Rolling Submissions
Application Due Date: June 8, 2026
Application Due Date: October 7, 2026
Application Due Date: February 8, 2027
Application Due Date: June 8, 2027
Application Due Date: October 7, 2027
Close Date: June 8, 2028

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