grant PA-25-306

NIH R21 Exploratory/Developmental Grant — Clinical Trial Required

This NIH Parent R21 funds exploratory, high-risk/high-reward biomedical, behavioral, or clinical research that must include one or more clinical trials and may lack extensive preliminary data. Projects should be novel and distinct from R01-style or long-term incremental studies; some participating Institutes/Centers only accept mechanistic clinical trials under this FOA, so applicants are enco…

The evolution and vitality of the biomedical, behavioral, and clinical sciences require a constant infusion of new ideas, techniques, and points of view. These may differ substantially from current thinking or practice and may not yet be supported by substantial preliminary data. Through the NIH…

Funding Source

Agency: National Institutes of Health

Awards & funding

Award Ceiling: $275,000

Eligibility

Regional Organizations
Public Housing Authorities/Indian Housing Authorities
Independent School Districts
U.S. Territory or Possession Governments
Indian/Native American Tribal Governments (Federally Recognized)
Special District Governments
City or Township Governments
County Governments
State Governments
For-Profit Organizations – Small Businesses
Nonprofits (Other than Institutions of Higher Education) – without 501(c)(3) IRS Status
Higher Education Institutions – Public/State Controlled Institutions of Higher Education
Faith-based or Community-based Organizations
Foreign Organizations / Non-domestic (non-U.S.) Entities

  • Foreign participation: Non-domestic (non-U.S.) entities (foreign organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are eligible. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
  • PD/PI eligibility: Any indi…

Dates

Rolling Submissions
Opportunity Released: December 18, 2024
Open Date: January 16, 2025
Application Due Date: February 16, 2026
Expiration Date: January 8, 2028

Supporting links

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