Scout | Notice of Special Interest (NOSI): Somatic Cell Gene Editing Therapies to Improve Transplantation Outcomes

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Notice of Special Interest (NOSI): Somatic Cell Gene Editing Therapies to Improve Transplantation Outcomes

This grant encourages partnerships between transplant immunologists and gene editing specialists to use SCGE technology in transplants. The goal is to prevent rejection, achieve transplant tolerance, extend the lifespan of transplanted organs, and enhance their function. Studies should involve human tissues or animal models and include modifications that reduce immune response and improve tran…

Source

Agency: National Institutes of Health

Sub-agency: National Institute of Allergy and Infectious Diseases

Dates

Opportunity Released: December 3, 2024

Keywords

gene editing

transplantation

somatic cell gene editing

transplant immunology

multidisciplinary collaboration

allograft survival

transplant tolerance

ex vivo modification

in vivo modification

graft immunogenicity

Supporting Links

Documents

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