Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)
This NIH NOFO funds milestone-driven, biphasic mechanistic research to identify person-specific factors (e.g., microbiome, immune status, sex, age, diet, genetics) that explain variable responses to probiotic interventions. The R61 phase supports observational or secondary-data studies to find host patterns linked to probiotic effects; the R33 phase tests causality in rigorous mechanistic stud…
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