Scout | PAR-24-294: NIH Blueprint Neurotherapeutics: SBIR U44 funding for biologic therapies for nervous/neuromuscular disorders, preclinical to Phase 1

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grant PAR-24-294

NIH Blueprint Neurotherapeutics: SBIR U44 funding for biologic therapies for nervous/neuromuscular disorders, preclinical to Phase 1

Summary

NIH’s BPN Biologics program funds small businesses to advance biologic therapies (e.g., antibodies, peptides, oligonucleotides, gene and cell therapies) for nervous and neuromuscular disorders. Using a milestone-driven U44 Fast-Track, projects can progress from lead optimization and IND-enabling work to optional first-in-human Phase 1 trials, with access to NIH guidance and optional CRO suppor…

The NIH Blueprint for Neuroscience Research is a collaborative framework through which 13 NIH Institutes, Centers, and Offices jointly support neuroscience research, with the aim of accelerating transformative discoveries for the nervous system in health, aging, and disease. For further informat…

Funding Source

Agency: National Institutes of Health

Sub-agency: National Institute of Neurological Disorders and Stroke

Phase: Phase II

Eligibility

For-Profit Organizations: United States Small Business Concerns (SBCs) only

Joint ventures that qualify as U.S. SBCs (each party must independently meet SBIR/STTR ownership/control requirements; foreign business participation in the JV must be <50%)

SBCs majority-owned by multiple venture capital operating companies, hedge funds, or private equity firms (SBIR-only; no single such firm may own >50% unless it itself qualifies as a U.S.-owned SBC)

Only United States Small Business Concerns (SBCs) are eligible to apply. Key SBIR/STTR small business eligibility criteria (must be met at time of Phase I and Phase II award):

Organized for profit with a place of business in the U.S.; operates primarily in the U.S. or makes a signif…

Dates

Opportunity Released: October 1, 2024

Open for Submission: October 1, 2024

Submission Deadline: August 18, 2027

Application Window Closes: August 18, 2027

Supporting links

National Institutes of Health

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