Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)
NIH is funding investigator-led projects to discover and optimize small-molecule chemical probes that work in living systems (in vivo) to study nervous system—especially novel brain targets relevant to mental health, addiction, vision, and aging. Applicants are expected to start from validated hit compounds and have a plan for chemical optimization and in vitro/in vivo bioassays, aiming to adv…
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