Scout | NIH: Discover In Vivo Chemical Probes for Brain Targets (R01, Clinical Trials Not Allowed)

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NIH: Discover In Vivo Chemical Probes for Brain Targets (R01, Clinical Trials Not Allowed)

This NIH NOFO supports research teams to discover and develop small-molecule chemical probes that work in living systems for novel nervous system or brain targets. Applicants are expected to already have validated starting hits for chemical optimization and bioassays for testing new analogs. Funding will prioritize projects that reveal meaningful insight into disease-relevant targets and biolo…

Source

Agency: National Institutes of Health

Dates

Open Date: May 4, 2026

Close Date: March 5, 2027

Eligibility

government

industry:research

nonprofit

small_business

tribal

university

For profit organizations other than small businesses

Native American tribal governments (Federally recognized)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Private institutions of higher education

State governments

Keywords

chemical probes

brain targets

small molecules

in vivo assays

nervous system

drug discovery

r01

nih

Supporting Links

Documents

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