In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains Exhibiting Embryonic or Perinatal Lethality or Subviability (R01 Clinical Trial Not Allowed)
This grant opportunity encourages research on embryonic lethal knockout (KO) mouse strains developed by the International Mouse Phenotyping Consortium (IMPC). The IMPC aims to catalog mammalian gene functions, aiding the understanding of human genetic variation. Currently, data is available for 8,260 knockout genes. The goal is to create null mutants and perform detailed phenotyping for every …
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