Prophylactics/Therapeutics for Neurotoxin Exposure
This grant opportunity seeks to develop a biological agent that can either prevent illness before exposure or treat symptoms after exposure to chemical warfare nerve agents, specifically G-type or V-type neurotoxins. The project is divided into three phases:
Phase I: Focuses on demonstrating the ability to perform assays for enzyme turnover rates that deactivat…
A biological agent is sought to prevent illness upon exposure to chemical warfare nerve agents, to include G-type or V- type neurotoxins, by either administering a prophylactic before anticipated exposure or administering a therapeutic after symptoms of exposure. Phase II will demonstrate robust…
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