Scout | Notice of Funding Opportunity (NOFO) for Clinical Trials of Orphan Products

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Notice of Funding Opportunity (NOFO) for Clinical Trials of Orphan Products

This grant opportunity is designed to fund clinical trials for orphan products aimed at treating rare diseases with unmet medical needs. It supports trials in any phase (1, 2, or 3) of product development, focusing on assessing the safety and/or effectiveness of medical products for new uses or updated labeling.

Source

Agency: National Institutes of Health

Award

Award Ceiling: $900,000

Dates

Letter of Intent Due Date: September 22, 2025

Application Due Date: October 21, 2025

Resubmission ONLY Application Due Date: May 19, 2026

Letter of Intent Due Date: September 21, 2026

Application Due Date: October 20, 2026

Resubmission ONLY Application Due Date: May 18, 2027

Letter of Intent Due Date: September 20, 2027

Application Due Date: October 19, 2027

Resubmission ONLY Application Due Date: May 16, 2028

Eligibility

government

nonprofit

small_business

tribal

university

School Districts: Independent School Districts

Housing Authorities: Public Housing Authorities/Indian Housing Authorities

Faith-based or Community-based Organizations

Regional Organizations

Foreign/Non-domestic Entities (Foreign Organizations)

Other (Unspecified)

Government: Local Governments (general)

Tribal Organizations (other than Federally recognized tribal governments)

Higher Education Institutions: Private Institutions of Higher Education

Nonprofits (Other than Institutions of Higher Education): without 501(c)(3) IRS Status

For-Profit Organizations: Other than Small Businesses

Keywords

orphan products

clinical trials

rare diseases

unmet medical needs

product development

safety evaluation

efficacy evaluation

new indication

labeling change

medical products

Supporting Links

Documents

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