Clinical Validation of Candidate Biomarkers for Neurological and Neuromuscular Disorders (U01)
This U01 cooperative agreement funds milestone-driven clinical validation of candidate biomarkers or biomarker signatures for neurological and neuromuscular disorders, supporting validation in one or two specified contexts of use. Applicants must demonstrate prior analytical validation and preliminary clinical evidence, propose multidisciplinary teams with regulatory/statistical expertise, and…
A biomarker is a defined characteristic that is measured as an indicator of a normal biological process, pathogenic process, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities are diverse, and can include ‘omics, imaging, behavioral, digital an…
Funding Source
Eligibility
Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed in applications from eligible domestic o…
Dates
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