Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)
This grant opportunity supports the development and validation of biomarkers to improve clinical trials and therapeutic development. It involves two phases: first, identifying or confirming candidate biomarkers using human samples or data; second, conducting clinical studies to validate their use in specific situations. The goal is to prepare biomarkers for final validation studies.
The purpose of this Notice of Funding Opportunity (NOFO) is to conduct proof of concept biomarker discovery and development studies followed by preliminary clinical validation to evaluate if the candidate biomarker or composite biomarker may be fit-for-purpose for use in clinical trials or clini…
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Non-domestic (non-U.S.) entities (foreign organizations) are NOT eligible to apply. Non-domestic (non-U.S.) components of U.S. organizations are NOT eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed within U.S. applications.
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