Scout | PAR-24-096: NIH funding to clinically validate biomarkers for neurological and neuromuscular disorders

This opportunity is no longer accepting applications.

grant PAR-24-096

NIH funding to clinically validate biomarkers for neurological and neuromuscular disorders

Summary

NINDS invites projects to clinically validate candidate biomarkers or biomarker signatures for neurological or neuromuscular conditions. Applicants must show preliminary clinical relevance and have a developed detection method ready for rigorous analytical and pre-analytical evaluation; awards are milestone-driven cooperative agreements and may include optional clinical trials. Results should …

A biomarker is a defined characteristic that is measured as an indicator of a normal biological process, pathogenic process, or responses to an exposure or intervention, including therapeutic interventions. Biomarker modalities are diverse, and can include ‘omics, imaging, behavioral, digital an…

Funding Source

Agency: National Institutes of Health

Sub-agency: National Institute of Neurological Disorders and Stroke

Phase: Phase II

Phase: Phase I

Awards & funding

Award Ceiling: $1.5M

Eligibility

U.S. SBC joint ventures that meet SBA SBIR/STTR eligibility and have <50% participation by foreign business entities

U.S. SBCs majority‑owned by multiple venture capital operating companies, hedge funds, or private equity firms (SBIR only; subject to SBA restrictions)

U.S. SBCs owned by an Indian tribe, Alaska Native Corporation (ANC), or Native Hawaiian Organization (NHO), or a wholly owned business entity of such

United States Small Business Concerns (SBCs) — for‑profit, U.S.-based entities with ≤500 employees (including affiliates), meeting SBA SBIR/STTR size and ownership/control criteria

Only United States Small Business Concerns (SBCs) are eligible to apply. Key SBA/NIH SBIR/STTR eligibility conditions include: (1) organized for profit; (2) place of business located in the U.S.; operates primarily in the U.S. or makes a significant contribution to the U.S. economy (taxes/use of…

Dates

Opportunity Released: January 22, 2024

Open for Submission: January 22, 2024

Submission Deadline: June 22, 2026

Application Window Closes: June 22, 2026

Supporting links

National Institutes of Health

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