Chemical Probes and Drugs for Modulating HIV Transcription in the Context of Substance Use Disorders (R01 Clinical Trial Not Allowed)
This grant opportunity aims to support research focusing on two main areas related to HIV and substance use disorder (SUD). Firstly, it seeks to identify targets and pathways to suppress HIV activity in the body, especially in the central nervous system of individuals with SUD. Secondly, it encourages the development of new small molecule drugs that can be used to suppress HIV transcription in…
HIV infection and substance use are comorbid conditions that bidirectionally and synergistically influence the deleterious outcomes in people who suffer from substance use disorders (SUD). The persistence and transcriptional reactivation of HIV lead to the development of neuropathological compl…
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