Scout | PAR-25-226: Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)

grant PAR-25-226

Seamless Early-Stage Clinical Drug Development (Phase 1 to 2a) for Novel therapeutic Agents for the Spectrum of Alzheimer's Disease (AD) and AD-related Dementias (ADRD) (UG3/UH3 Clinical Trial Required)

This grant opportunity focuses on supporting early-stage clinical trials for new treatments targeting Alzheimer's disease and related dementias. It combines initial phase 1 and early phase 1b/2a trials into one process. Eligible interventions should target mechanisms other than amyloid and tau proteins and aim to improve cognitive and/or neuropsychiatric symptoms across different stages of the…

Source

Agency: National Institutes of Health

Sub-agency: National Institute on Aging

Dates

Opportunity Released: November 22, 2024

Eligibility

Government

Research

Nonprofit

Small business

Tribal

University

Higher Education Institutions: Private Institutions of Higher Education

Nonprofit Organizations (Other than Institutions of Higher Education): without 501(c)(3) IRS Status

Independent School Districts

For-Profit Organizations: For-Profit Organizations (Other than Small Businesses)

Public Housing Authorities/Indian Housing Authorities

Native American Tribal Organizations (other than Federally recognized tribal governments)

Eligible Agencies of the Federal Government

U.S. Territory or Possession

Faith-based or Community-based Organizations

Regional Organizations

Non-domestic (non-U.S.) Entities (Foreign Organizations)

Non-domestic (non-U.S.) components of U.S. Organizations

Keywords

Alzheimer's

dementia

clinical trials

pharmacological interventions

cognitive symptoms

neuropsychiatric symptoms

phase 1 trials

phase 2a trials

non-amyloid mechanisms

non-tau mechanisms

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Documents

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