Scout | Rational Design of Vaccines Against Hepatitis C Virus (U19 Clinical Trial Not Allowed)

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Rational Design of Vaccines Against Hepatitis C Virus (U19 Clinical Trial Not Allowed)

What this funding is for: To create a consortium of Research Centers that design, optimize, evaluate, and advance broadly protective hepatitis C virus (HCV) vaccines, including completing IND-enabling studies to move the best candidates into clinical testing.
Why it matters: HCV causes chronic infection in most cases and leads to serious liver disease. Despite effectiv…

Agency: Department of Health and Human Services

Hepatitis C vaccine

HCV vaccine development

broadly neutralizing antibodies

structural vaccinology

E1/E2 glycoprotein antigen design

immunogenicity and T-cell responses

IND-enabling preclinical studies

correlates of protection

animal models for HCV

NIAID U19

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