Developing PBPK Model-Based Mechanistic IVIVCs for Long Acting Injectable Suspensions and Implants (U01) Clinical Trial Optional
This opportunity supports research to build physiologically based pharmacokinetic (PBPK) models that link in vitro data to in vivo performance (mechanistic IVIVCs) for long-acting injectable crystalline suspensions and polymer-based implants. Projects will account for formulation attributes and product-specific release mechanisms, using targeted in vitro and in vivo experiments and validating …
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