Mechanistic Investigations into ADRD Multiple Etiology Dementias (R01 - Clinical Trial Not Allowed)
This grant opportunity seeks research projects focused on understanding how multiple protein-related pathologies contribute to worsening neurodegenerative diseases. Applicants should study at least two related pathologies and may include additional risk factors or co-morbidities. The aim is to explore cellular and molecular interactions in the brain across different regions and times, examinin…
This NOFO would support investigations with a minimum of two relevant co-pathologies (e.g., tau, alpha-synuclein, TDP-43, TMEM106B, vascular), with optional risk factors and co-morbidities, to identify cellular and molecular mechanisms of how/why multi-proteinopathy interactions drive worsening …
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