FY26 ALS Research Program Therapeutic Development Award for preclinical lead validation and IND-enabling studies
This award funds product-driven ALS research that takes therapeutic candidates from preclinical validation through FDA IND-enabling studies. Projects must start with lead compounds and already show proof-of-concept efficacy in at least one appropriate preclinical ALS model (cellular and/or whole-animal). Strong emphasis is placed on mechanism-specific, predictive biomarkers and target engageme…
Summary: The fiscal year 2026 (FY26) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Development Award (TDA) supports research ranging from preclinical validation of therapeutic leads through U.S. Food and Drug Administration (FDA) Investigational New Drug (IN…
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