FY26 ALS Research Program Therapeutic Development Award for preclinical-to-IND drug studies
This award funds mechanism-driven ALS therapeutic development, from preclinical validation of leads through FDA IND-enabling work. Projects must start with lead compounds in hand and already show proof-of-concept efficacy in relevant ALS whole-animal and cellular models. A key requirement is parallel development of mechanism-specific, predictive biomarkers for target engagement and pharmacodyn…
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